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UK Clinicians and Patients Refine Best Practices for GLP-1 Weight-Loss Jabs

New guidance on weight training, nutrition, monitoring tackles skin laxity, metabolic slowdown, gallbladder issues under ongoing safety reviews

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Overview

  • Around 1.5 million Britons are using GLP-1 receptor agonists such as Mounjaro through NHS primary care or private clinics under the NHS obesity plan.
  • The MHRA is investigating hundreds of pancreatitis cases and gallbladder complications, including at least ten deaths linked to these injections.
  • Leading practitioners warn that undereating can slow resting metabolic rate and stall weight loss, with signs including hair loss, muscle aches and sensitivity to cold.
  • Users like ‘Foxy’ credit weightlifting regimens with helping preserve muscle mass and reduce loose skin during rapid, clinically backed weight loss.
  • Clinicians recommend tailored nutritional protocols, regular scans and blood tests to optimize treatment outcomes and flag adverse effects early.