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UK Biobank Launches Largest Proteomics Study to Transform Disease Research

The groundbreaking project will analyze 5,400 proteins in 600,000 samples, offering unprecedented insights into disease mechanisms and early detection.

  • The UK Biobank study will measure 5,400 proteins in 600,000 blood samples, including follow-up samples from 100,000 participants over 15 years.
  • This initiative aims to revolutionize diagnostics, prognostics, and drug discovery by integrating proteomic, genetic, and imaging data.
  • Pilot data from 2023 linked over 14,000 genetic variants to protein changes, uncovering potential biomarkers for diseases like cancer, dementia, and autoimmune conditions.
  • The study is backed by 14 pharmaceutical companies, with initial data releases expected in 2026 and the full dataset available by 2027.
  • Researchers anticipate the findings will enable earlier disease detection, personalized treatments, and the repurposing of existing drugs for new conditions.
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