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UCLA Study Ties Supportive Marriages to Lower Obesity Risk Through Brain–Gut–Oxytocin Signals

Researchers describe the findings as preliminary due to a small, cross-sectional sample.

Overview

  • Published in Gut Microbes, the study assessed nearly 100 Los Angeles adults using brain imaging during food cues, fecal metabolomics, plasma oxytocin tests, BMI, and behavioral evaluations.
  • Married participants who reported strong emotional support had lower BMI and fewer food-addiction behaviors than those in less supportive marriages.
  • Brain scans showed heightened dorsolateral prefrontal cortex activity when viewing food in the high-support married group, a pattern not seen in unmarried participants.
  • Supportive marriages were linked to higher plasma oxytocin and beneficial changes in tryptophan-related gut metabolites tied to inflammation, immune function, energy balance, and brain health.
  • The authors suggest oxytocin may connect self-control circuits with gut metabolism and they urge larger, longitudinal, more diverse studies to test causality.