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UCLA Achieves World’s First Successful Human Bladder Transplant

The groundbreaking procedure, paired with a kidney transplant, restores renal function and eliminates dialysis for a 41-year-old patient.

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L’hôpital Ronald Reagan UCLA Medical Center à Los Angeles, en Californie, où a été réalisée cette prouesse.

Overview

  • UCLA surgeons performed the first-ever successful human bladder transplant, overcoming long-standing medical challenges.
  • The procedure combined a kidney transplant with a bladder graft from the same donor, ensuring compatibility and functionality.
  • Patient Oscar Larrainzar, who had been on dialysis for seven years due to cancer-related bladder and kidney removal, immediately regained full renal function post-surgery.
  • The innovative technique addresses previous barriers to bladder transplantation, such as vascularization and accessibility, which left patients reliant on risk-prone alternatives like intestinal reconstructions or external ostomy bags.
  • Following over four years of preparation, the team is now initiating clinical trials to evaluate the safety and long-term efficacy of the procedure.