Overview

• Uppsala University researchers report that younger men with type 2 diabetes fare worse than peers with type 1 diabetes on early cardiovascular and mortality outcomes.
• Males with type 2 diabetes under 50 faced a 51% higher overall cardiovascular risk, a 2.4-fold higher heart attack risk, and a 2.2-fold higher heart failure risk compared with males with type 1 diabetes.
• Across women, most outcomes were worse with type 1 diabetes, with cardiovascular mortality 34% lower and all-cause mortality 19% lower in women with type 2 diabetes, with differences significant over age 50.
• The analysis covered 404,026 adults aged 18–84, including 38,351 with type 1 diabetes and 365,675 with type 2 diabetes, with 233,858 males and 170,168 females.
• A study author cited earlier onset and longer exposure in women with type 1 diabetes and heavier cardiometabolic risk burdens with later diagnosis in younger men with type 2 diabetes as likely contributors.