Overview

• Researchers with the International Brain Laboratory published companion studies on September 3 detailing a whole‑brain, single‑cell activity map recorded during a visual choice task in mice.
• Across 12 labs using Neuropixels probes, the team recorded 621,733 neurons spanning 279 brain areas in 139 mice, then applied quality control to analyze 75,708 well‑isolated units.
• The data show decision‑related signals and rewards are distributed across many regions rather than confined to a single decision center.
• A second paper reports that prior expectations are encoded widely, including in early sensory relays such as the thalamus, indicating predictive signals shape processing from the outset.
• All datasets, analysis code, and protocols are openly available, with researchers highlighting implications for studying conditions like schizophrenia and autism.