Particle.news

Download on the App Store

Trump Warns Pregnant Women to Limit Tylenol as FDA Begins Label Review and Leucovorin Is Touted

Medical experts say the evidence on prenatal acetaminophen and autism remains inconclusive, warning that guidance must not discourage treating fever in pregnancy.

Overview

  • At a White House event, President Trump urged expectant mothers to avoid acetaminophen unless medically necessary and said clinicians should use the lowest effective dose for the shortest duration.
  • HHS said the FDA will start a safety‑label update process for acetaminophen products and issue a physician letter advising clinicians to consider minimizing use during pregnancy for routine low‑grade fevers.
  • The administration highlighted leucovorin, a folinic acid used for cancer and some anemias, as a potential therapy for autism symptoms, though current evidence comes from small studies and lacks large, rigorous trials.
  • Researchers and major medical groups disputed a causal link, pointing to mixed findings and a large 2024 Swedish sibling study that found no increased autism risk from prenatal acetaminophen exposure.
  • Tylenol maker Kenvue rejected any connection and its shares fell sharply on Monday, finishing down about 7% after earlier intraday losses.