Particle.news

Download on the App Store

Trump to Announce Autism Guidance on Prenatal Tylenol Risk and Leucovorin Therapy

Major medical groups say claims of causation outpace the evidence.

Overview

  • At an Oval Office event Monday, President Trump is slated to speak alongside HHS Secretary Robert F. Kennedy Jr. and CMS Administrator Mehmet Oz after previewing that his team has “found an answer to autism.”
  • Reporting from the Wall Street Journal and Washington Post indicates the administration will advise against routine acetaminophen use in pregnancy, limiting it to high fevers, and will highlight low maternal folate as a risk factor.
  • The announcement is expected to promote leucovorin (folinic acid) as a potential symptom‑reducing therapy for autism, reflecting small early trials that researchers caution are preliminary.
  • Kenvue, the maker of Tylenol, and the American College of Obstetricians and Gynecologists say prudent acetaminophen use remains safe in pregnancy and warn that discouraging it could push patients toward riskier options or untreated fever.
  • Published research is mixed, with some meta‑analyses reporting associations between prenatal acetaminophen exposure and autism, while a large 2024 Swedish sibling‑controlled study found no causal link; the underlying HHS/NIH report has not been fully released.