Overview

• The executive order adds $50 million to the Childhood Cancer Data Initiative, doubling its annual budget to $100 million to support AI-ready pediatric cancer data and research.
• The MAHA Commission will work with the White House Office of Science and Technology Policy to apply AI to diagnosis, clinical trials, treatments and prevention, with NIH planning competitive research calls and private-sector engagement without naming vendors.
• HHS is directed to integrate AI into interoperability efforts so electronic health records and claims data can inform research and trial design, while parents retain control of children’s health information.
• Officials say the effort builds on the 2019 CCDI data infrastructure to address fragmented datasets and enable tools such as models that predict treatment responses and minimize side effects.
• Trump signed the order in the Oval Office with HHS Secretary Robert F. Kennedy Jr., NIH Director Jay Bhattacharya and NCI Director Anthony Letai present, as multiple outlets highlighted tension with proposed NIH and NCI cuts still before Congress.