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Trump Sets Oval Office Autism Briefing as Reports Point to Tylenol Warning, Leucovorin Push

Major medical guidance says acetaminophen remains appropriate in pregnancy when used as directed.

Overview

  • President Trump said he will announce autism-related findings Monday and noted HHS Secretary Robert F. Kennedy Jr. and CMS Administrator Dr. Mehmet Oz will join him in the Oval Office.
  • The Washington Post and earlier Wall Street Journal reporting say officials plan to link prenatal acetaminophen use to autism risk and to highlight leucovorin as a potential therapy.
  • Reporting indicates federal health officials are expected to advise avoiding Tylenol early in pregnancy unless treating a fever, challenging prevailing clinical guidance.
  • Tylenol maker Kenvue rejected any causal link and cited regulators and clinicians who consider acetaminophen safe in pregnancy as needed; experts warn untreated fever and pain carry risks.
  • Research remains mixed, with a large 2024 JAMA sibling-controlled study finding no association, smaller studies and meta-analyses suggesting associations without proving causation, and early leucovorin trials described as preliminary.