Overview

• The executive order instructs federal agencies to deploy artificial intelligence across diagnosis, clinical trials, treatment and prevention for childhood and young adult cancers.
• NIH will add $50 million in competitive awards to leverage and improve existing Childhood Cancer Data Initiative resources, with further investments planned.
• The plan tasks the MAHA Commission and White House science advisers to strengthen data infrastructure and modernize trial design and access using AI tools.
• Officials underscore that pediatric cancer is the leading disease-related killer of U.S. children and that incidence has risen more than 40% since 1975.
• The announcement follows a 2026 proposal to cut NCI funding by 37%, a plan not adopted in current House and Senate drafts.