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Trump Gives Pharma Titans 60-Day Ultimatum to Slash U.S. Drug Prices to International Levels

The ultimatum leverages an executive order to force U.S. drug prices down to the lowest rates paid by other developed nations under threat of using “every tool in our arsenal.”

White House press secretary Karoline Leavitt holds up a letter from President Donald Trump to Eli Lilly CEO David Ricks during a press briefing at the White House in Washington, Thursday, July 31, 2025. (AP Photo/Mark Schiefelbein)

Overview

  • On July 31, Trump sent identical letters to the CEOs of 17 leading pharmaceutical companies, setting a Sept. 29 deadline to adopt most-favored-nation pricing for U.S. sales
  • The letters direct companies to offer Medicaid patients global lowest prices, guarantee the same rates for all newly launched drugs and redirect extra revenues earned overseas back to American consumers
  • Trump warned that firms refusing to comply will face “every tool in our arsenal,” though legal experts have questioned the scope of presidential authority to enforce private-market price mandates
  • The industry trade group PhRMA argued that mandatory price cuts could undermine U.S. pharmaceutical leadership and harm patients and workers
  • White House Press Secretary Karoline Leavitt previewed the letters at a briefing and Trump amplified the push by posting each letter on his TRUTH Social platform