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Trump Administration to Advise Caution on Tylenol Early in Pregnancy Over Autism Risk

The move comes as officials prepare to spotlight leucovorin as a potential therapy despite medical guidance that finds no proven causal link.

Overview

  • Multiple outlets report the administration will recommend avoiding routine acetaminophen use in early pregnancy except to treat fever, citing a possible association with autism.
  • HHS plans to highlight leucovorin (folinic acid) as an investigational option for some autism symptoms, based on small early trials that have not established efficacy or approval.
  • HHS Secretary Robert F. Kennedy Jr., alongside FDA commissioner Marty Makary and NIH director Jay Bhattacharya, is steering the effort that President Trump has previewed publicly.
  • NIH officials say a separate data-science program has funded 13 research teams to study causes and treatments and will proceed independently of Monday’s messaging.
  • Kenvue, Tylenol’s maker, disputes any causal link and met with HHS leaders, while experts cite a 2024 Swedish cohort finding no relationship and contrast it with a 2025 HarvardMount Sinai review reporting non-causal associations.