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Trump Administration Set to Warn on Prenatal Tylenol, Cite Possible Autism Link

Major medical authorities maintain acetaminophen is considered safe pending proof of a causal link.

Overview

  • Officials are expected to advise avoiding routine acetaminophen use in early pregnancy unless treating fever, according to multiple reports.
  • The White House plans to highlight leucovorin as a potential autism therapy under study, which is not standard of care.
  • Research remains contested, with a 2025 HarvardMount Sinai review noting associations and a 2024 Swedish sibling-controlled study finding no causal relationship.
  • Kenvue, maker of Tylenol, rejects any connection to autism and its CEO met HHS leaders to challenge the planned risk messaging.
  • NIH is launching a separate data-science autism initiative funding 13 teams to investigate causes, evaluate treatments, and validate prior studies.