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Trump Administration Prepares for Second Round of Indirect Nuclear Talks with Iran in Rome

The negotiations, set for April 19, come as tensions rise over Iran's uranium enrichment and Trump's threats of military action if no deal is reached.

An Iranian newspaper with a cover photo of Iran's Foreign Minister Abbas Araqchi and U.S. Middle East envoy Steve Witkoff, is seen in Tehran, Iran, April 12, 2025. Majid Asgaripour/WANA (West Asia News Agency) via REUTERS/File Photo
Iran's Foreign Minister Abbas Araqchi attends a press conference following a meeting with Russia's Foreign Minister Sergei Lavrov in Moscow, Russia, April 18, 2025. Tatyana Makeyeva/Pool via REUTERS
US President Donald Trump takes questions from members of the media as he meets with Italian Prime Minister Giorgia Meloni in the Oval Office of the White House in Washington, DC, on April 17, 2025. Italy's Prime Minister Giorgia Meloni meets with Donald Trump Thursday in Washington, hoping a personal charm offensive can help convince the US president to cut a more favourable deal on EU tariffs.
An Iranian newspaper with a cover photo of Iran's Foreign Minister Abbas Araqchi and U.S. Middle East envoy Steve Witkoff, is seen in Tehran, Iran, April 12, 2025. Majid Asgaripour/WANA (West Asia News Agency) via REUTERS/File Photo

Overview

  • The U.S. and Iran are scheduled for a second round of indirect nuclear negotiations in Rome on April 19, following constructive talks in Oman last week.
  • President Trump has reiterated that preventing Iran from obtaining a nuclear weapon is a key red line, with sanctions relief offered as part of potential agreements.
  • Iran has exceeded the uranium enrichment limits set by the 2015 nuclear deal, approaching weapons-grade levels, raising international concerns over proliferation risks.
  • Trump has threatened to bomb Iran's nuclear sites if negotiations fail, while also signaling a preference for a diplomatic resolution.
  • The U.S. negotiating team is led by Steve Witkoff, a Trump confidant with no prior diplomatic experience, while Iran remains wary of the talks and insists on indirect dialogue.