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Trained Dogs Detect Parkinson’s Smell With Up to 98% Specificity

Validation of skin swab biomarkers this July points to multicenter trials after refinement of sample collection and training protocols.

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Parkinson's Disease Has a Smell That Some Dogs Can Detect
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Overview

  • Published on July 15 in the Journal of Parkinson’s Disease, the trial showed dogs identified Parkinson’s samples with up to 80% sensitivity and 98% specificity.
  • Two dogs—Bumper, a golden retriever, and Peanut, a black Labrador—successfully completed training out of ten candidates after exposure to more than 200 skin swab samples.
  • The study confirmed a distinct sebum-based olfactory signature linked to Parkinson’s and was conducted by the University of Bristol with Medical Detection Dogs and the University of Manchester.
  • Researchers are refining swab collection and canine training protocols to address variability and are planning larger multicenter validation studies.
  • Funded by the Michael J. Fox Foundation and Parkinson’s UK, this work seeks to establish a non-invasive early screening method for a disease that currently lacks pre-diagnostic tests.