Overview
- Kick-off is at 20:00 GMT at Tottenham Hotspur Stadium, with live coverage on TNT Sports 1 via discovery+.
- Tottenham have added Mathys Tel to their Champions League squad in place of injured Dominic Solanke under the UEFA long-term injury rule, with Randal Kolo Muani a doubt.
- Left-back Destiny Udogie is out until January with a hamstring issue, several key players remain sidelined, and Brennan Johnson is described as touch and go.
- Micky van de Ven, Richarlison and Kolo Muani face a one-match ban if booked, while Xavi Simons is expected to feature after a goal and an assist against Brentford.
- Spurs are unbeaten in 22 European home matches and have kept three home Champions League clean sheets this season, whereas Slavia are winless in the league phase with just two goals and none away; bookmakers list Tottenham as clear favourites.