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Top CDC Vaccine Expert Resigns as Agency Lacks Director After HHS Guidance Shift

The resignation follows Robert F. Kennedy Jr.’s unilateral revision of COVID-19 vaccine guidance for children and pregnant women; the ACIP is due to meet June 25–27 to reassess recommendations.

A CDC official resigned on Friday following HHS changes to Covid-19 vaccine recommendations.
Photo illustration: Brendan Lynch/Axios. Photo: Tasos Katopodis/Getty Images
MIAMI, FLORIDA - MAY 29: In this photo illustration,  Pfizer-BioNTech COVID-19 (L) and Moderna COVID-19 vaccines fill their syringes at Borinquen Health Care Center on May 29, 2025 in Miami, Florida. Health and Human Services Secretary Robert F. Kennedy Jr. announced that he will no longer recommend that healthy children and pregnant people get COVID-19 shots. (Photo illustration by Joe Raedle/Getty Images)
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Overview

  • Dr. Lakshmi Panagiotakopoulos, co-leader of the CDC’s COVID-19 vaccine working group, resigned in early June, expressing that recent policy changes prevented her from protecting vulnerable populations.
  • In May, HHS Secretary Robert F. Kennedy Jr. bypassed the Advisory Committee on Immunization Practices to remove routine COVID-19 vaccine recommendations for healthy children and pregnant women.
  • The CDC subsequently updated its schedule to allow healthy children to receive COVID-19 vaccines under a shared clinical decision-making model while dropping its pregnancy recommendation.
  • With no confirmed director in place, CDC Chief of Staff Matthew Buzzelli has assumed some director duties despite his lack of a public health background.
  • The Advisory Committee on Immunization Practices is scheduled to convene June 25–27 to deliberate and vote on COVID-19 vaccine recommendations, potentially restoring expert-driven guidance.