Overview
- Six teams advanced directly to the quarterfinals: Toluca, Tigres, Cruz Azul, América, Monterrey and Chivas.
- The Play-In will be single-match ties hosted by the higher seed—Xolos (7) vs Juárez (8) and Pachuca (9) vs Pumas (10)—scheduled for November 19–23.
- By seeding, two quarterfinal series are already set: Cruz Azul vs Chivas and América vs Monterrey.
- Liga MX’s 'regla de menores' requires at least 1,170 minutes per tournament by players under 22, and every club complied in Apertura 2025.
- Bolavip published ChatGPT-based predictions favoring Xolos over Juárez and Pachuca over Pumas, with any projected bracket dependent on Play-In results.