Titans and Colts Prepare for Crucial AFC South Clash

Both teams face quarterback uncertainties and injury challenges as they vie for a key divisional win.

Tennessee Titans return from their bye week aiming to improve their 1-3 record in their first AFC South game this season.
Indianapolis Colts, currently 2-3, are dealing with significant injuries, including key players like Jonathan Taylor and Michael Pittman Jr.
Quarterbacks Will Levis and Anthony Richardson are tied for the NFL lead in interceptions, each throwing six this season.
The Titans boast the NFL's top-ranked defense in total yards allowed, while the Colts have struggled defensively, allowing the most yards per game.
Betting lines have shifted in favor of the Titans, now 2.5-point favorites, despite quarterback uncertainties on both sides.