Overview
- Portland earned a 2-2 draw in regulation when Gage Guerra headed in an equalizer in the eighth minute of stoppage time.
 - Antony Alves Santos struck the winning penalty after Portland’s Kristoffer Velde scored, with Marcus Ingvartsen missing and Jeppe Tverskov hitting the crossbar for San Diego.
 - Hirving “Chucky” Lozano made his first MLS playoff appearance at halftime and gave San Diego a 2-1 lead with a 51st-minute goal.
 - San Diego’s Amahl Pellegrino had earlier tied the match following a collision that saw teammate dos Santos apparently knocked unconscious and taken off by ambulance.
 - The series stands 1-1 heading into the Nov. 9 finale in San Diego, with Timbers goalkeeper James Pantemis making three saves and Pablo Sisniega stopping two for SDFC.