Overview
- Tigres beat Atlético San Luis 3-1 at Estadio Universitario to reach 36 points and take the provisional lead.
- João Pedro put San Luis ahead early before Ángel Correa leveled for the hosts before halftime.
- Marco Farfán made it 2-1 after the break, and San Luis went down to ten men when Jahaziel Marchand was sent off in the 64th minute.
- Second-half substitute Diego Laínez sealed the result with the third goal, and a late fourth for Tigres was overturned by VAR for an offside on Nicolás Ibáñez.
- Juan Brunetta was held out to avoid a fifth yellow card, and Tigres will open the quarterfinals on Nov. 26 or 27 with a Clásico Regio in that round no longer possible.