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Three Hand and Nail Changes Linked to Advanced Liver Disease, Health Sources Warn

Health groups say these late-stage signs warrant medical evaluation.

Overview

  • UK outlets are amplifying guidance from the Cleveland Clinic, the NHS and the British Liver Trust highlighting nail clubbing, blotchy red palms and Terry's nails as possible warning signs.
  • Liver disease often shows no early symptoms, with later bile-flow problems leading to jaundice, dark urine, pale stools, itchy skin, weight loss and other systemic effects, according to the Cleveland Clinic.
  • Nail clubbing tied to cirrhosis may start in the thumb and index finger before spreading, a change thought to reflect increased blood flow that widens fingertip vessels.
  • Palmar erythema occurs in about 23% of people with cirrhosis and can be harder to detect on brown or black skin, the coverage notes from Medical News Today and the NHS.
  • Terry's nails look largely white with a narrow colored band at the tip and were historically observed in most cirrhosis patients; other skin signs include spider angiomas, petechiae, xanthelasma and easy bruising.