Overview

• In a JAMA Network Open study published August 5, 2025, 61 women with bulimia nervosa were randomized to guided internet-based CBT or usual care for 12 weeks.
• Participants receiving the online therapy recorded about 10 fewer total binge and compensatory episodes over the period compared with those in usual care.
• Remission at 12 weeks reached up to 55% with the guided program versus 13% with usual care, indicating a clinically meaningful advantage.
• More than three quarters of participants said they would return to the online program, reflecting high satisfaction with the therapist-supported modules adapted for Japanese patients.
• The authors describe this as the first trial of its kind in Asia and urge health-system integration and insurance coverage, noting the small, women-only sample and the need for larger, longer studies.