The Apothecary Diaries Season 2 Debuts With New Themes and Anticipated Storylines

The historical mystery anime returns with fresh opening and ending themes, teasing deeper character dynamics and expanded narratives.

The Apothecary Diaries Season 2 premiered as part of the Winter 2025 anime lineup and is now streaming on Crunchyroll.
The new opening theme, 'Hyakka Ryoran (Splendid Bounty)' by Lilas Ikuta, and ending theme, 'Shiawase no Recipe' by HIRAIDAI, have been praised for their visuals and music.
The season will adapt Volumes 3 and 4 of the light novel, introducing new mysteries, political intrigue, and evolving relationships between Maomao and Jinshi.
A key moment teased in the opening is the popular 'frog scene,' which fans of the manga and novels recognize as pivotal to character development.
Season 2 builds on the success of the first season, offering a blend of medical mysteries, slow-burn romance, and high-stakes palace drama.