Overview
- San Francisco (5-2) visits Houston (2-4) in Week 8 on FOX, with the 49ers favored by 1.5 points, and the series at 4-1 in San Francisco’s favor.
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- Brock Purdy (toe) could miss a fourth straight game, making Mac Jones the likely 49ers starter, while Texans WR Nico Collins is in the concussion protocol and WR Christian Kirk’s status is uncertain.
- The 49ers lead the NFL at 271.3 passing yards per game, while the Texans allow just 179.0 passing yards per game, ranking fifth; Houston is plus-4 in turnover differential and San Francisco is minus-5.
- Houston coach DeMeco Ryans faces former boss Kyle Shanahan for the first time as head coaches, with the last meeting between the teams a 23-7 49ers win on Jan. 2, 2022.