Overview
- Josh Allen was sacked a career-high eight times for 70 yards and took 12 hits, failed to score on the ground, and remains tied with Cam Newton at 75 career rushing touchdowns for a quarterback.
- Calen Bullock forced three turnovers, picking Allen twice and sealing the win with an interception at the Houston 9 with 24 seconds left after an earlier pick-six was erased by a penalty.
- Will Anderson Jr. recorded 2.5 sacks and Danielle Hunter added two as Houston's top-ranked defense controlled the line of scrimmage throughout the night.
- With C.J. Stroud out due to a concussion, Davis Mills threw for 153 yards and two first-half touchdowns to move to 3-0 as the Texans' starter.
- Buffalo fell to 7-4 after a late 4th-and-27 hook-and-lateral kept the drive alive before a false start set up the game-ending interception, while Houston improved to 6-5.