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Teva, Amerisource Pull 580,000+ Prazosin Bottles as FDA Flags Nitrosamine Contamination

Patients are being told to check lot numbers with pharmacists instead of stopping treatment.

Overview

  • The FDA says affected prazosin hydrochloride lots tested above acceptable intake limits for the nitrosamine identified as N‑nitroso Prazosin Impurity C under its CPCA framework.
  • Regulators classified the recall as Class II, indicating a low likelihood of serious harm but requiring removal of compromised product.
  • Teva Pharmaceuticals USA and Amerisource Health Services initiated a voluntary nationwide recall covering multiple lots across the United States.
  • The action includes 1 mg, 2 mg and 5 mg capsule strengths, with manufacturers and distributors instructed to pull listed lots from the market.
  • Prazosin is used to lower blood pressure and is sometimes prescribed for PTSD‑related nightmares, so clinicians advise obtaining replacements rather than interrupting therapy.