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Tellurium Nanowire Retinal Implant Restores Vision in Blind Mice, Enhances Infrared Sensitivity in Macaques

Developers aim to cut production costs for human trials following successful safety tests in macaques

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Using imaging and electrophysiological recording, the team found that implanting the prosthesis into genetically blind mice restored reflexes in the pupil and evoked neuron firing in the visual cortex. Credit: Neuroscience News
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Overview

  • A three-dimensional lattice of tellurium nanowires converts visible and near-infrared light into electrical signals for retinal stimulation
  • Implanted in genetically blind mice, the device restored pupil reflexes and enabled navigation and pattern recognition on par with sighted controls
  • Safety and biocompatibility studies in crab-eating macaques showed no adverse reactions and revealed heightened near-infrared detection in sighted subjects
  • The nanowire architecture overcomes electrical interference issues of prior prostheses and boosts contrast perception under low-light conditions
  • Researchers are now prioritizing cost-effective manufacturing methods to scale up production ahead of human clinical testing