Teddi Mellencamp Says She Is Struggling as Treatment Shrinks Tumors in Stage‑4 Cancer Fight

Overview

• Speaking on her Two T’s in a Pod podcast, Mellencamp said she is currently struggling and coping with severe PTSD, spending extensive time in therapy, resting and with family.
• She reported that immunotherapy has significantly reduced her tumors and said the situation feels like a cloud beginning to lift, describing it as as good as it can be.
• She recounted an emergency head surgery in February 2025 that removed more tumors than expected, after which doctors found additional lesions in her brain and lung.
• John Mellencamp recently described her as really sick with cancer affecting the brain and said he regularly travels to Los Angeles to visit her.
• He said on the Today Show that he begged her to return to Indiana during recovery, while she has continued her public life and ongoing treatment in Los Angeles.