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Teddi Mellencamp Embraces Hope With 50-50 Prognosis, Pauses Immunotherapy

Debilitating treatment side effects prompted Mellencamp to pause immunotherapy, relying on her father’s daily care to maintain her strength

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John Mellencamp performs during the Grammy Hall Of Fame Gala at The Beverly Hilton on May 16, 2025, in Beverly Hills, California.
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Overview

  • On July 29, Mellencamp appeared on The Jamie Kern Lima Show and described her decision to focus on belief over fear in facing stage 4 melanoma.
  • She revealed that doctors have given her roughly a 50% chance of surviving cancer that has metastasized to her brain and lungs.
  • Persistent side effects from her three-weekly immunotherapy treatments in July left her too weak to manage basic tasks and led her medical team to halt further doses for recovery.
  • Scans have shown her tumors shrinking, and she plans to resume immunotherapy after a restorative protocol of rest and steroids.
  • Her father, musician John Mellencamp, has arranged around-the-clock nursing care and checks in daily to support her both physically and emotionally.