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Tata Memorial to Routinely Offer Ultra-High Dose MIBG Therapy After Teen’s Remission

ACTREC will offer the 800 mCi therapy at Rs 7–8 lakh with ongoing monitoring to refine patient eligibility

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The boy, who was first diagnosed in 2022 at age 14, had undergone a stem cell transplant but suffered a relapse earlier this year, leaving doctors with limited options.

Overview

  • The 17-year-old patient, who relapsed after a 2022 stem cell transplant, received the 800 mCi dose on May 5 and has been discharged cancer-free
  • At Rs 7–8 lakh, the treatment costs about one-tenth of anti-GD2 immunotherapy regimens, improving access for families facing steep care expenses
  • Approval from the Atomic Energy Regulatory Board followed a detailed radiation-safety simulation report and the construction of a specialized ward with 41 hot beds and sealed waste systems
  • This inaugural high-dose protocol triples the previous 300 mCi cap and has demonstrated a 25–35% long-term cure rate in high-risk relapsed neuroblastoma
  • Long-term follow-up will track patient outcomes and inform expansion of the therapy to other high-risk neuroblastoma cases nationwide