Overview
- Argentina recorded 36,702 syphilis cases through epidemiological week 44 of 2025, a 20.5% increase versus the same period in 2024 and likely to challenge last year’s record total.
- Young people bear the brunt of the epidemic, with 76% of cases in those aged 15–39 and the highest rates in the 20–24 and 25–29 age groups.
- The burden is geographically uneven, with the Central region leading and Córdoba posting the highest provincial rate at 220.3 per 100,000 in 2024.
- Some provinces show sharp year-on-year jumps in 2025, including Neuquén (+110%), Entre Ríos (+72%) and Tierra del Fuego (+57%), while others report declines.
- Mexico reports a parallel rise with 18,083 confirmed acquired cases by week 44 of 2025, up 17.52% year over year, concentrated in Jalisco and Mexico City, as officials and experts highlight prevention gaps such as reduced condom use and reinfections.