Overview
- Argentina reported 36,702 syphilis cases in the first 44 weeks of 2025, a 20.5% year-over-year increase after 2024 set the highest annual total on record with 36,917.
- Cases in Argentina are concentrated among people aged 15 to 39, with the highest rates in the 20–24 and 25–29 age groups.
- The Centro region accounted for 61.3% of Argentina’s 2024 cases and Córdoba posted the highest rate nationally, while Neuquén, Entre Ríos and Tierra del Fuego showed the sharpest recent rises.
- Mexico logged 18,083 confirmed acquired syphilis cases through week 44 of 2025, up 17.52% from a year earlier, with Jalisco and Mexico City reporting the largest totals.
- Officials highlight prevention shortfalls and frequent HIV coinfection, as ministries step up surveillance, deploy rapid tests and benzathine penicillin, and promote primary-level screening.