Overview

• Published August 28 in Nature Human Behaviour, the study reassessed 248 meta-analyses spanning 200 trials and more than 10,000 participants.
• No high-quality evidence supported efficacy for any complementary, alternative or integrative intervention on core or associated autism symptoms.
• Safety data were scarce, with fewer than half of the interventions reporting acceptability, tolerability or adverse events.
• Researchers launched a public evidence platform at ebiact-database.com to help autistic people, families and clinicians navigate the findings.
• Authors urged shared decision-making and reliance on rigorous randomized trials rather than isolated, low-quality studies; the work was funded by France’s ANR.