Overview

• Published in eClinicalMedicine on August 2, 2025, the study tracked over 270,000 Swedes born between 1920 and 1922 from age 70 for up to 30 years via national health registers.
• Centenarians experienced a leveling off of disease accumulation around age 90, often with disorders restricted to a single organ system and fewer concurrent conditions.
• Cardiovascular diseases were both less common and appeared later in life among those who reached 100.
• Neuropsychiatric disorders occurred at lower rates in centenarians compared with earlier decedents.
• The results reveal a distinct aging curve that challenges the belief that longer lives inevitably carry higher disease burdens.