Overview

• University of Mississippi researchers detailed the coating strategy in Advanced Healthcare Materials, using glyco ionic liquids on drug-loaded nanoparticles.
• The sugar-like surface is designed to exploit overexpressed glucose transporters on triple-negative breast cancer cells to boost cellular uptake.
• The team reports the coated therapies can hitch rides on red and white blood cells, helping ferry the medication toward tumors.
• Mississippi’s high burden shaped the project’s focus, with a 2024 analysis showing 37% of treated breast cancers were triple-negative, far above the national average.
• The study is NIH-supported under grant P20GM130460.