Study Unveils Proteins Influencing Human Brain Connectivity

Research identifies hundreds of proteins that contribute to individual differences in brain region communication, offering insights into neural function and potential disease pathways.

• The study integrates molecular and neuroimaging data to map biochemical mechanisms affecting brain connectivity.
• Researchers used dendritic spine morphometry to connect molecular data with brain-wide networks.
• The findings highlight proteins involved in synaptic structures, energy metabolism, and RNA processing.
• The research utilized data from the ROSMAP study, involving elderly participants' postmortem brain samples.
• This approach could inform new strategies for understanding and potentially treating neurodegenerative diseases.

3 Articles

GEN Neuroscience News Technology Networks