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Study Traces SARS-CoV-2 Origins to Wildlife Trade, Reinforcing Natural Spillover Theory

New genetic analysis shows the virus likely traveled from bats in Western China or Northern Laos to Wuhan via wildlife trade, challenging lab-leak theories.

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Overview

  • Researchers from UC San Diego and collaborators analyzed non-recombining regions of the SARS-CoV-2 genome to trace its evolutionary path.
  • The study found that the virus's ancestor left bat populations in Western China or Northern Laos 5–7 years before the Wuhan outbreak, too quickly for natural bat migration.
  • Evidence suggests the virus likely traveled to Wuhan through wildlife trade intermediaries, similar to the 2002 SARS outbreak involving palm civets and raccoon dogs.
  • The findings undermine lab-leak theories by highlighting parallels between SARS-CoV-2 and the natural emergence of SARS-CoV-1.
  • Scientists emphasize the need for continued surveillance of bat populations to predict and mitigate future zoonotic disease outbreaks.