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yesterday

Study Reveals Persistent Cognitive and Functional Declines in ICU Survivors with PICS

New findings highlight frailty, age, and baseline cognition as key predictors of Post-Intensive Care Syndrome, affecting over half of ICU survivors and worsening long-term outcomes.

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Overview

  • More than 50% of ICU survivors experience Post-Intensive Care Syndrome (PICS), characterized by lasting cognitive and functional impairments.
  • Researchers identified two recovery trajectories, with one marked by persistent deficits in cognition and daily living activities over a year post-ICU.
  • Baseline frailty, older age, and pre-illness cognitive function are significant predictors of PICS, while illness severity and delirium duration were not associated.
  • Patients in the PICS trajectory face lower one-year survival rates (51.3%) compared to peers with normal recovery trajectories (78%).
  • The study emphasizes the need for predictive tools and targeted interventions, such as cognitive, physical, and occupational therapy, to improve patient outcomes.