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Study Reveals Gut Microbiota's Role in Stress Regulation via Circadian Rhythms

Researchers identify specific gut bacteria that modulate stress responses, paving the way for new mental health therapies.

  • The study highlights the interaction between gut microbiota and the body's circadian rhythms in regulating stress responses.
  • Depletion of gut bacteria leads to hyperactivation of the hypothalamic-pituitary-adrenal (HPA) axis, affecting stress responsivity throughout the day.
  • Limosilactobacillus reuteri is identified as a key bacterium influencing stress hormone secretion in a time-dependent manner.
  • Findings suggest potential for microbiome-based therapies to manage stress-related mental health conditions like anxiety and depression.
  • Maintaining a healthy gut microbiome is crucial for stress regulation, especially in modern lifestyles that disrupt natural circadian cycles.
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