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Study Maps Thousands of DNA Variants That Shape Personality

The consortium’s pooled analysis finds DNA influences personality at the group level and shows current genetic measures cannot reliably predict individuals.

Overview

  • A multinational team published a Nature paper reporting 1,260 genetic variants linked to the five major personality traits and estimating that more than 16,000 common variants influence each trait.
  • The results come from harmonized data contributed by 46 research groups with combined samples large enough to detect many tiny genetic effects across traits.
  • Common genetic variants explained roughly 5 to 9 percent of variation in personality, which means current genetic scores offer only modest predictive power for behavior.
  • Within-family comparisons and analyses across ages, regions, test types, and rater types showed most associations are not due to family-shared environment and are broadly consistent, though agreeableness was less consistent.
  • The study found genetic overlap between personality and health outcomes and urges larger, more ancestrally diverse samples while stressing these findings are tools for research, not grounds for predicting or judging individuals.