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Study Links Oral Bacteria in Coronary Plaques to Possible Heart Attack Triggers

Clinical practice remains unchanged pending confirmation of causality.

Overview

  • Researchers reported in the Journal of the American Heart Association that coronary plaques from 121 sudden-death autopsies and 96 surgical patients frequently contained genetic material from oral bacteria.
  • Viridans group Streptococci were the most commonly detected organisms, with targeted antibody work identifying biofilm-like structures within arterial tissue.
  • The authors observed bacterial dispersal in some ruptured plaques and propose that dormant plaque biofilms may reactivate and ignite local inflammation leading to thrombosis.
  • Independent cardiologists called the findings intriguing yet preliminary, emphasizing that the evidence is associative and requires replication and validation of live bacteria before changing care.
  • Experts advise maintaining strong oral hygiene, treating dental infections promptly, and staying current on influenza, COVID-19, and pneumococcal vaccinations, noting no approved vaccine protects against strep viridans.