Study Links MRI Contrast Agents to Toxic Nanoparticle Formation in Rare Cases

University of New Mexico researchers identify oxalic acid in common foods as a trigger for gadolinium nanoparticle formation, potentially causing severe health conditions.

• Recent research confirms that oxalic acid, found in foods like spinach and sweet potatoes, can bind with gadolinium from MRI contrast agents, forming toxic nanoparticles.
• These nanoparticles may contribute to nephrogenic systemic fibrosis, a rare but severe condition that can result in organ damage and even death after a single MRI dose.
• While most patients experience mild or no side effects, gadolinium deposits have been detected in tissues, blood, and urine years after exposure in some cases.
• Experts are now recommending a reassessment of pre-scan dietary guidelines, including avoiding vitamin C supplements, to mitigate risks associated with gadolinium contrast agents.
• The findings underscore the need to better understand individual metabolic differences and dietary impacts to improve MRI safety protocols.

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