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Study Links Long-Term Antidepressant Use to Severe Withdrawal Risks

UCL research reveals users on antidepressants for over two years face a tenfold higher risk of severe and prolonged withdrawal, emphasizing the importance of supervised tapering.

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Overview

  • University College London researchers found that patients taking antidepressants for over two years are ten times more likely to experience severe withdrawal symptoms than short-term users.
  • Symptoms include psychological effects like anxiety, worsened mood, and agitation, as well as physical issues such as dizziness, headaches, and nausea, often lasting months or even over a year.
  • The study reported that 79% of long-term users struggled to discontinue antidepressants, compared to 38% of the overall group surveyed.
  • Experts recommend gradual tapering of doses under the guidance of informed health professionals to mitigate withdrawal severity and duration.
  • Approximately 8.7 million people in England are prescribed antidepressants, with half of users taking the medication for at least a year, highlighting the widespread implications of these findings.