Study Links Germ Cells to Gender Differences in Lifespan

Research on killifish reveals that cells developing into sperm and eggs influence longevity, with potential implications for humans.

Female killifish live longer than males, but removing germ cells equalizes their lifespans.
Germ cell removal decreases estrogen signaling in females, increasing growth but reducing health maintenance.
Males without germ cells show improved muscle, skin, and bone health due to increased vitamin D activation.
Administering vitamin D extends the lifespan of both male and female killifish.
Findings suggest germ cells and vitamin D signaling could play roles in human aging and longevity.