Overview
- Female killifish live longer than males, but removing germ cells equalizes their lifespans.
- Germ cell removal decreases estrogen signaling in females, increasing growth but reducing health maintenance.
- Males without germ cells show improved muscle, skin, and bone health due to increased vitamin D activation.
- Administering vitamin D extends the lifespan of both male and female killifish.
- Findings suggest germ cells and vitamin D signaling could play roles in human aging and longevity.