Overview
- Researchers compared 5,758 vaccinated with 5,758 unvaccinated pediatric atopic dermatitis patients matched on demographics and health history, excluding prior COVID-19 and major comorbidities.
- Vaccinated children showed lower rates of respiratory and skin infections, including otitis media, pneumonia, bronchitis, bronchiolitis, sinusitis, upper respiratory infections, impetigo, and molluscum contagiosum.
- Risks of allergic outcomes were reduced in the vaccinated group, with fewer cases of asthma, allergic rhinitis, contact dermatitis, and food-related anaphylaxis reported.
- Time-to-event analyses indicated delayed onset for several conditions after vaccination, including allergic rhinitis, viral infections, and ear infections.
- Findings were presented at the ACAAI 2025 meeting in Orlando and published in Annals of Allergy Asthma & Immunology, with authors noting observational evidence and calling for prospective and mechanistic studies.