Overview

• A study of over 500,000 UK Biobank participants identified 56 modifiable non-clinical risk factors for sudden cardiac arrest.
• Moderate consumption of champagne or white wine was associated with a 30% reduction in cardiac arrest risk, challenging the emphasis on red wine's cardioprotective benefits.
• Lifestyle factors including higher fruit intake, positive mood, healthy weight, and blood pressure control were found to be key protective measures.
• Researchers estimate that 40% to 63% of sudden cardiac arrest cases could be avoided by addressing these modifiable factors.
• The study utilized an exposome-wide methodology and Mendelian randomization to strengthen causal links, highlighting the complexity of alcohol’s effects on heart health.