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Study Links BPA Replacements in Food Labels to Cellular Changes, Prompting Health Canada Review

Experiments found fat buildup with altered gene activity in human ovarian cells exposed to four common label chemicals.

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Overview

  • The peer-reviewed findings were published in Toxicological Sciences and examined substances used in price stickers and packaging.
  • TGSA, D-8, PF-201 and BPS induced lipid droplet accumulation in KGN granulosa cells, with the strongest effects seen for TGSA and D-8.
  • Transcriptomic analyses identified shifts in genes involved in cell growth and DNA repair following exposure.
  • Health Canada added all four chemicals to a list for further investigation after the study’s release.
  • Researchers emphasize that in vitro signals do not prove harm in people and advise precautionary steps such as removing labels and plastic wrap and choosing items from the top of display stacks.