Study Links Aspartame to Increased Heart Disease Risk in Mice

New research identifies a potential mechanism connecting the artificial sweetener to arterial plaque buildup and inflammation in animal models.

Researchers found that aspartame consumption in mice led to higher insulin levels, increased inflammation, and fatty plaque buildup in arteries.
The study identified the immune signal molecule CX3CL1 as a key factor in the harmful effects, which traps immune cells and promotes inflammation.
The experiments involved genetically modified mice fed aspartame doses equivalent to three cans of diet soda daily for 12 weeks.
Experts caution that the findings, while significant, are based on animal models and may not directly translate to human health risks.
The research highlights the need for further studies to determine the long-term cardiovascular effects of artificial sweeteners in humans.